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United States

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製品番号: HY-187552

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F050

F050 is an orally active intracellular platelet calcium ([Ca²⁺]i) inhibitor. F050 inhibits thrombin-induced elevation of intracellular calcium in platelets. F050 inhibits platelet aggregation induced by CaCl₂, arachidonic acid, collagen, adenosine diphosphate (ADP), and thrombin across multiple species, and reduces thrombus formation in an extracorporeal circulation thrombosis model in guinea pigs. F050 also inhibits hypotonic NaCl-induced erythrocyte hemolysis and is used in research on thrombotic diseases.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 186835-06-3
分子式: C₂₁H₂₀O
分子量:288.38

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

F050 構造式

CAS 番号: 186835-06-3

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

F050 inhibits CaCl₂-, arachidonic acid-, collagen-, ADP-, and thrombin-induced platelet aggregation in guinea pig, rabbit, and rat platelets in vitro, with a wider spectrum of actions than Acetylsalicylic acid (HY-14654)^[1].
F050 inhibits hypotonic NaCl-induced hemolysis of guinea pig erythrocytes in vitro^[1].
F050 inhibits thrombin-induced increases in [Ca²⁺]ᵢ in guinea pig platelets in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 186835-06-3
分子量 288.38
分子式 C₂₁H₂₀O
SMILES

OCCCC1=CC(C2=CC=CC=C2)=C(C3=CC=CC=C3)C=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Hongou K, et al. Antithrombotic effects of 3-([1:1',2':1"]-3'-terphenyl)propanol in animals. Arzneimittel-Forschung. 1997 Oct;47(10):1104-8.

[2]. Chen C, et al. Structure, rheological, thermal conductive and electrical insulating properties of high-performance hybrid epoxy/nanosilica/AgNWs nanocomposites[J]. Composites Science and Technology, 2016, 128: 207-214.

[3]. Hamel E, et al. Cornigerine, a potent antimitotic Colchicum alkaloid of unusual structure: interactions with tubulin[J]. Biochemical pharmacology, 1988, 37(12): 2445-2449.

Calculators

モル濃度計算機

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分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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