FCH-2296413
Based on 1 Customer Validation
FCH-2296413 is a potent and selective hydroxycarboxylic acid receptor (HCAR) agonist with an EC50 of 4.4-8.6 nM. FCH-2296413 exhibits analgesic activity and can be used for the research of peripheral pain-related diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 96.37%
- CAS 番号: 1229028-63-0
- 分子式: C8H8N6
- 分子量:188.19
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
0.21 μM
Compound: (+/-)17a
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Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay
Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay
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[PMID: 20363624] |
化学情報
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CAS 番号 1229028-63-0
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性状 Solid
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分子量 188.19
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分子式 C8H8N6
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Color Light yellow to light brown
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SMILES
C1(C2=NNC3=C2CC4CC34)=NN=NN1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : 15 mg/mL (79.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3138 mL | 26.5689 mL | 53.1378 mL | 132.8445 mL |
| 5 mM | 1.0628 mL | 5.3138 mL | 10.6276 mL | 26.5689 mL | |
| 10 mM | 0.5314 mL | 2.6569 mL | 5.3138 mL | 13.2844 mL | |
| 15 mM | 0.3543 mL | 1.7713 mL | 3.5425 mL | 8.8563 mL | |
| 20 mM | 0.2657 mL | 1.3284 mL | 2.6569 mL | 6.6422 mL | |
| 25 mM | 0.2126 mL | 1.0628 mL | 2.1255 mL | 5.3138 mL | |
| 30 mM | 0.1771 mL | 0.8856 mL | 1.7713 mL | 4.4281 mL | |
| 40 mM | 0.1328 mL | 0.6642 mL | 1.3284 mL | 3.3211 mL | |
| 50 mM | 0.1063 mL | 0.5314 mL | 1.0628 mL | 2.6569 mL | |
| 60 mM | 0.0886 mL | 0.4428 mL | 0.8856 mL | 2.2141 mL |
FCH-2296413 関連分類
HY-403593 関連分類
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