Formycin triphosphate
Formycin triphosphate is a fluorescent ATP analog. Formycin triphosphate is a competitive inhibitor of chicken liver pyruvate carboxylase with respect to ATP. Formycin triphosphate can be used in research on human colon cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 16409-13-5
- 分子式: C10H16N5O13P3
- 分子量:507.18
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Formycin triphosphate partially substitutes for ATP in E. coli RNA polymerase assays, supporting RNA synthesis up to 47-68% on native DNA templates and up to 56%, 94%, and 67% on poly d (A-T), poly d (T-C)·d (A-G), and poly d (T-G)·d (A-C) templates, respectively[6].
Formycin triphosphate is faithfully incorporated by E. coli RNA polymerase in place of ATP, generating poly (F-U), poly (F-C), and poly (F-G) with alternating FpUp, FpCp, and FpGp sequences[6].
Formycin triphosphate does not substitute for UTP, CTP, or GTP in E. coli RNA polymerase reactions directed by poly d (T-C)·d (A-G) or poly d (T-G)·d (A-C)[6].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 16409-13-5
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分子量 507.18
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分子式 C10H16N5O13P3
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SMILES
NC1=C2C(C([C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@H]3O)=NN2)=NC=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)