Ganoderiol F
Based on 1 Customer Validation
Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines.
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- 純度: 99.85%
- CAS 番号: 114567-47-4
- 分子式: C30H46O3
- 分子量:454.68
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF S-180 | IC50 |
7.1 μg/mL
Compound: 15
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Cytotoxicity against mouse S180 cells
Cytotoxicity against mouse S180 cells
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[PMID: 23092389] |
| HEK293 | EC50 |
5 μM
Compound: 14
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Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay
Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay
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[PMID: 22014750] |
| HeLa | IC50 |
5 μM
Compound: 15
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Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
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[PMID: 23092389] |
| Hep 3B2 | IC50 |
25.3 μM
Compound: 15
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Cytotoxicity against human Hep3B cells
Cytotoxicity against human Hep3B cells
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[PMID: 23092389] |
| HepG2 | IC50 |
17 μM
Compound: 15
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Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
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[PMID: 23092389] |
| HepG2 | IC50 |
20.7 μM
Compound: 2
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Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
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[PMID: 24974349] |
| Huh-7 | IC50 |
8.5 μM
Compound: 15
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Cytotoxicity against human HuH7 cells
Cytotoxicity against human HuH7 cells
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[PMID: 23092389] |
| K562 | IC50 |
4 μM
Compound: 15
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Cytotoxicity against human K562 cells
Cytotoxicity against human K562 cells
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[PMID: 23092389] |
| K562 | IC50 |
54.9 μM
Compound: 22
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Cytotoxicity against human K562 cells by MTT method
Cytotoxicity against human K562 cells by MTT method
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[PMID: 26287401] |
| Lewis lung carcinoma cell line | IC50 |
2 μg/mL
Compound: 15
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Cytotoxicity against mouse LLC cells
Cytotoxicity against mouse LLC cells
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[PMID: 23092389] |
| PC-3 | IC50 |
79.5 μM
Compound: 22
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Cytotoxicity against human PC3 cells by MTT method
Cytotoxicity against human PC3 cells by MTT method
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[PMID: 26287401] |
| RAW264.7 | IC50 |
36 μM
Compound: 7
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method
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[PMID: 23357630] |
| T47D | IC50 |
3 μg/mL
Compound: 15
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Cytotoxicity against human T47D cells
Cytotoxicity against human T47D cells
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[PMID: 23092389] |
化学情報
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CAS 番号 114567-47-4
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性状 Solid
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分子量 454.68
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分子式 C30H46O3
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Color White to off-white
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SMILES
C[C@]1(CC[C@]2([H])[C@H](C)CC/C=C(CO)/CO)C(C3=CC[C@@]12C)=CC[C@](C(C)4C)([H])[C@@]3(CCC4=O)C
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Structure Classification
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Initial Source
Ganoderma amboinense
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Ganoderiol F 関連分類
HY-N3924 関連分類
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