LY6G6C - lymphocyte antigen 6 family member G6C Gene

Also Known as G6c; NG24; C6orf24

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 80740

About LY6G6C

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,718,648-31,721,746 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele and 91 orthologues. Restricted expression toward skin (RPKM 160.9).

Summary

LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 Amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]

LY6G6C Products (1)

mRNA Protein Name
NM_025261.3 NP_079537.1 lymphocyte antigen 6 complex locus protein G6c precursor
Protein Preferred Names Protein Names

lymphocyte antigen 6 complex locus protein G6c

  • lymphocyte antigen 6 complex, locus G6C

LY6G6C Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
LY6G6C O95867 SLC41A2 Homo sapiens Q96JW4
Validated Y2H
32296183
Intra
LY6G6C O95867 SLC38A7 Homo sapiens Q9NVC3
Validated Y2H
32296183
Intra
LY6G6C O95867 C4orf3 Homo sapiens Q8WVX3-2
Validated Y2H
32296183
Intra
LY6G6C O95867 TMEM203 Homo sapiens Q969S6
Validated Y2H
32296183
Intra
LY6G6C O95867 SLC39A2 Homo sapiens Q9NP94
Validated Y2H
32296183
Intra
LY6G6C O95867 YIPF6 Homo sapiens Q96EC8
Validated Y2H
32296183
Intra
LY6G6C O95867 UBE2J1 Homo sapiens Q9Y385
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Lynch Syndrome I

  • Lynch Syndrome 1

  • Colorectal Cancer, Hereditary Nonpolyposis, Type 1

  • HNPCC1

  • Fcc1

  • Lynch Syndrome Ii

  • Colon Cancer, Familial Nonpolyposis, Type 1

  • Coca1

  • Familial Nonpolyposis Colon Cancer Type 1

  • Hereditary Nonpolyposis Colorectal Cancer Type 1

  • Hereditary Non-Polyposis Colorectal Cancer 1

  • Hereditary Non-Polyposis Colorectal Cancer 3

  • Hnpcc3

  • Lynch Cancer Family Syndrome

  • Lynch Syndrome

  • Lynch Syndrome Type I

  • Lynch Syndrome Type Ii

  • Cancer, Colorectal, Nonpolyposis, Hereditary, Type 1

  • Hereditary Nonpolyposis Colorectal Cancer

  • Colorectal Cancer, Hereditary Nonpolyposis, Type 3

  • Hereditary Non-Polyposis Colon Cancer Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS07898 LY6G6C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus LY6G6C VGNC VGNC:63334
Mus musculus LY6G6C MGD MGI:2148930
Rattus norvegicus LY6G6C RGD RGD:1302999
Macaca mulatta LY6G6C VGNC VGNC:74285
Bos taurus LY6G6C VGNC VGNC:31090
Canis familiaris LY6G6C VGNC VGNC:42875
Others LY6G6C NCBI