Geninthiocin
Geninthiocin is a thiopeptide with antibacterial and antifungal activities. Geninthiocin is a tipA promoter.
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- CAS 番号: 158792-27-9
- 分子式: C50H49N15O15S
- 分子量:1132.08
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Geninthiocin is active against a variety of Gram-positive bacteria (MICs = 0.2-4 µg/mL), the Gram-negative bacterium C. violaceum (MIC = 19 µg/mL), and the fungus M. hiemalis (MIC = 38 µg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 158792-27-9
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分子量 1132.08
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分子式 C50H49N15O15S
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SMILES
NC(C(NC(C(NC(C1=CC=C(C2=NC(C(N[C@@](C(N/C(C3=NC(C(NC(C(N[C@H](C(NC(C4=NC(C(NC(C(NC(C5=NC6=CO5)=C)=O)=C)=O)=C(O4)C)=C)=O)C(C)(O)C)=O)=C)=O)=CO3)=C\C)=O)([H])[C@H](O)C)=O)=CS2)C6=N1)=O)=C)=O)=C)=O
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Structure Classification
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Initial Source
Streptomyces sp
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Appadurai Muthamil Iniyan, et al. Ala-geninthiocin, a new broad spectrum thiopeptide antibiotic, produced by a marine Streptomyces sp. ICN19. J Antibiot (Tokyo). 2019 Feb;72(2):99-105. [Content Brief]
[2]. B S Yun, et al. Microbial metabolites with tipA promoter inducing activity. II. Geninthiocin, a novel thiopeptide produced by Streptomyces sp. DD84. J Antibiot (Tokyo). 1994 Sep;47(9):969-75. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)