country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-121611

Copy Link Print Information

HI-236

HI-236 is a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase.? HI-236 inhibits HIV activity (wild type HTLV_IIB IC₅₀p24 < 0.001 μM).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 233271-65-3
分子式: C₁₆H₁₈BrN₃O₂S
分子量:396.30

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

HI-236 構造式

CAS 番号: 233271-65-3

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

HI-236 is a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase.? HI-236 inhibits HIV activity (wild type HTLV_IIB IC₅₀p24 < 0.001 μM)^[1].

IC₅₀ & Target

wild type HTLV_IIB IC₅₀p24 <0.001 μM)^[1]

HIV アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	EC₅₀	0.042 μM Compound: HI-236	Antiviral activity against HIV1 3B in MT2 cells assessed as inhibition of viral-mediated T-cell death by MTT method Antiviral activity against HIV1 3B in MT2 cells assessed as inhibition of viral-mediated T-cell death by MTT method	[PMID: 17317163]
MT2	IC₅₀	>1 μM Compound: HI-236	Cytotoxicity against human MT2 cells Cytotoxicity against human MT2 cells	[PMID: 17317163]
MT2	CC₅₀	1 μM Compound: HI-236	Cytotoxicity against mock-infected human MT2 cells after 5 days by MTT assay Cytotoxicity against mock-infected human MT2 cells after 5 days by MTT assay	[PMID: 18996020]
MT2	EC₅₀	0.048 μM Compound: HI-236	Antiviral activity against nevirapine-resistant HIV1 3B infected in human MT2 cells assessed as inhibition of viral replication after 5 days by MTT assay Antiviral activity against nevirapine-resistant HIV1 3B infected in human MT2 cells assessed as inhibition of viral replication after 5 days by MTT assay	[PMID: 18996020]
MT2	EC₅₀	1200 nM Compound: HI-236	Antiviral activity against nevirapine-resistant HIV1 with reverse transcriptase Y181C mutation in human MT2 cells assessed as inhibition of viral replication after 5 days by MTT assay Antiviral activity against nevirapine-resistant HIV1 with reverse transcriptase Y181C mutation in human MT2 cells assessed as inhibition of viral replication after 5 days by MTT assay	[PMID: 18996020]
MT2	CC₅₀	18 μM Compound: HI-236	Cytotoxicity against HIV1 Y181C mutant infected human MT2 cells after 5 days by MTT assay Cytotoxicity against HIV1 Y181C mutant infected human MT2 cells after 5 days by MTT assay	[PMID: 18996020]
MT2	CC₅₀	>1 μM Compound: HI-236	Cytotoxicity against human MT2 cells after 5 days by MTT assay Cytotoxicity against human MT2 cells after 5 days by MTT assay	[PMID: 20605472]
MT2	EC₅₀	0.042 μM Compound: HI-236	Antiviral activity against HIV1 3B infected in human MT-2 cells assessed as inhibition of viral-mediated cell death after 5 days by MTT assay Antiviral activity against HIV1 3B infected in human MT-2 cells assessed as inhibition of viral-mediated cell death after 5 days by MTT assay	[PMID: 20605472]

化学情報

CAS 番号 233271-65-3
分子量 396.30
分子式 C₁₆H₁₈BrN₃O₂S
SMILES

S=C(NC1=NC=C(C=C1)Br)NCCC2=CC(OC)=CC=C2OC
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (264 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Sudbeck, E. A, et al. N'-(5-bromo-2-pyridyl)- N -[2-(2,5-dimethoxyphenyl)ethyl]thiourea. Acta Crystallographica Section C Crystal Structure Communications, 55(12), 2122–2124. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ

Amount: USD 0.00

生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献

製品名:
製品番号:
数量:
日本の代理先をお選びください:

製品名:
CAS 番号:
生物種:
純度:
数量:

HI-236

HIV アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

HI-236 関連分類

HY-121611 関連分類