Imidazenil
Based on 1 Customer Validation
Imidazenil is a partial positive allosteric modulator of GABAA receptors with anxiolytic, antipanic and anticonvulsant activities.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.95%
- CAS 番号: 151271-08-8
- 分子式: C18H12BrFN4O
- 分子量:399.22
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Membrane Transporter/Ion Channel Compound Library
HY-L011
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Neuronal Signaling Compound Library
HY-L013
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Neurotransmitter Receptor Compound Library
HY-L062
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Anti-Alzheimer's Disease Compound Library
HY-L069
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Anti-Parkinson's Disease Compound Library
HY-L085
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Neurodegenerative Disease-related Compound Library
HY-L086
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GABA Receptor Compound Library
HY-L120
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Membrane Protein-targeted Compound Library
HY-L149
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Membrane Receptor-targeted Compound Library
HY-L150
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Ion Channel Compound Library
HY-L166
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Allosteric Modulators (AMs) Compound Library
HY-L170
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MCE Bioactive Compound Library
HY-L001V
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
化学情報
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CAS 番号 151271-08-8
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性状 Solid
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分子量 399.22
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分子式 C18H12BrFN4O
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Color White to off-white
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SMILES
O=C(C1=C2CN=C(C3=C(Br)C=CC=C3)C4=C(C=CC(F)=C4)N2C=N1)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (125.24 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
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- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Giusti P, Ducić I, Puia G, et al. Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors. J Pharmacol Exp Ther. 1993;266(2):1018-1028. [Content Brief]
[2]. Thompson DM, Auta J, Guidotti A, Costa E. Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys. J Pharmacol Exp Ther. 1995;273(3):1307-1312. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5049 mL | 12.5244 mL | 25.0488 mL | 62.6221 mL |
| 5 mM | 0.5010 mL | 2.5049 mL | 5.0098 mL | 12.5244 mL | |
| 10 mM | 0.2505 mL | 1.2524 mL | 2.5049 mL | 6.2622 mL | |
| 15 mM | 0.1670 mL | 0.8350 mL | 1.6699 mL | 4.1748 mL | |
| 20 mM | 0.1252 mL | 0.6262 mL | 1.2524 mL | 3.1311 mL | |
| 25 mM | 0.1002 mL | 0.5010 mL | 1.0020 mL | 2.5049 mL | |
| 30 mM | 0.0835 mL | 0.4175 mL | 0.8350 mL | 2.0874 mL | |
| 40 mM | 0.0626 mL | 0.3131 mL | 0.6262 mL | 1.5656 mL | |
| 50 mM | 0.0501 mL | 0.2505 mL | 0.5010 mL | 1.2524 mL | |
| 60 mM | 0.0417 mL | 0.2087 mL | 0.4175 mL | 1.0437 mL | |
| 80 mM | 0.0313 mL | 0.1566 mL | 0.3131 mL | 0.7828 mL | |
| 100 mM | 0.0250 mL | 0.1252 mL | 0.2505 mL | 0.6262 mL |
Imidazenil 関連分類
HY-121393 関連分類
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