Insecticidal agent 42
Insecticidal agent 42 is an insecticide. Insecticidal agent 42 inhibits AChE, leading to acetylcholine accumulation and disruption of neurotransmission. Insecticidal agent 42 binds to the active pocket of AChBP, interfering with neural signaling pathways. Insecticidal agent 42 inhibits Ca2+, Mg2+-ATPase and Na+, K+-ATPase. Insecticidal agent 42 disrupts neuronal homeostasis, causing insect death, and exhibits systemic root-to-stem transport. Insecticidal agent 42 can be used for insecticidal research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C17H17ClN4O4S
- 分子量:408.86
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
AChE |
体内実験
Insecticidal agent 42 (10 mg/L; 48 h) exhibits high control efficacy against M. crassicauda in pot experiments, achieving 79.2% mortality at 10 mg/L[1].
Insecticidal agent 42 (12-36 h) exerts its insecticidal effect by inhibiting AChE activity and interfering with neurotransmission in M. crassicauda[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Megoura crassicauda (wingless individuals from a colony established from a field population and maintained in the laboratory for over 50 generations on broad bean (Vicia faba L.) seedlings)[1]
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Dosage:100, 10, and 1 mg/L
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Administration:spray application; mortality assessed at 48 h; root-dip
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Result:Exhibited an LC50 = 1.83 mg/L against M. crassicauda after 48 h of application.
Exhibited an LC50 of 4.63 mg/L in the systemic activity assessment via the root-dip method.
化学情報
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分子量 408.86
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分子式 C17H17ClN4O4S
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SMILES
O=C1C(CNC(OC(C)C)=O)=C([O-])[N+](CC2=CN=C(Cl)S2)=C3C=CC=CN31
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- Insecticidal agent 42
- Insecticidal agent42
- Insecticidal agent-42
- Insecticide
- Cholinesterase (ChE)
- nAChR
- Na+/K+ ATPase
- Proton Pump
- Ca2+
- Mg2+-ATPase
- nicotinic acetylcholine receptor
- Ls-AChBP
- acetylcholine-binding protein
- glutathione S-transferase
- M. crassicauda
- acetylcholinesterase
- Apis mellifera
- Na+
- K+-ATPase
- carboxylesterase
- Inhibitor
- inhibitor
- inhibit