J1-1
J1-1 is an inhibitor of ICMT with an IC50 of 1.0 μM and has anticancer activity.
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- CAS 番号: 1244769-10-5
- 分子式: C25H32N2O
- 分子量:376.53
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
IC50: 1.0 μM (ICMT)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
21.2 μM
Compound: 1-2
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by colorimetric tetrazolium assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by colorimetric tetrazolium assay
|
[PMID: 20809634] |
| Sf9 | IC50 |
1 μM
Compound: 1-2
|
Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting
Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting
|
[PMID: 20809634] |
化学情報
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CAS 番号 1244769-10-5
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分子量 376.53
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分子式 C25H32N2O
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SMILES
O=C(N)CC1=CN(CCCCCCCC)C2=C1C=C(C3=CC=CC=C3C)C=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)