Kynuramine
Kynuramine is an endogenous amine that serves as a fluorescent substrate and probe for plasma amine oxidase.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 363-36-0
- 分子式: C9H12N2O
- 分子量:164.20
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
Kynuramine inhibits both presynaptic and postsynaptic α-adrenoceptors in vitro[2].
Kynuramine has been shown to act as a partial agonist on serotonin receptors in dog cerebral arteries[2].
Kynuramine (20 μg/mL) causes a small contraction of the ileum but failed to alter the twitch response to cholinergic stimulation[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Kynuramine (1.25-5.0 mg/kg; i.v.; single does) increases heart rate and blood pressure in rats[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Female rats[3].
-
Dosage:0.064, 0.32, 1.6 or 8 μg.
-
Administration:Intraventricular injection; single does.
-
Result:Produced facilitation of lordosis behavior.
-
Animal Model:Male rats (about 200g)[4].
-
Dosage:1.25, 2.5 and 5.0 mg/kg.
-
Administration:Intravenous injection; single does.
-
Result:Promoted heart rate and blood pressure.
化学情報
-
CAS 番号 363-36-0
-
分子量 164.20
-
分子式 C9H12N2O
-
SMILES
O=C(CCN)C1=CC=CC=C1N
-
別名
Kynurenamine
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. J B Massey, et al. Kynuramine, a fluorescent substrate and probe of plasma amine oxidase. J Biol Chem. 1977 Nov 25;252(22):8081-4. [Content Brief]
[2]. T D Johnson, An alpha-adrenoceptor inhibitory action of kynuramine. Eur J Pharmacol. 1981 Jul 10;72(4):351-6. [Content Brief]
[3]. S D Mendelson, et al. Intraventricular administration of l-kynurenine and kynuramine facilitates lordosis in the female rat. Eur J Pharmacol. 1987 Oct 27;142(3):447-51. [Content Brief]
[4]. T D Johnson, et al. Blood pressure and heart rate effects of kynuramine in pithed rats. Eur J Pharmacol. 1983 Feb 18;87(2-3):323-6. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Kynuramine 関連分類
HY-119395 関連分類
Powered by Bioz