L-Lactaldehyde
L-Lactaldehyde ((2S)-Hydroxypropanal) is a chiral aldehyde, metabolic intermediate, and enzyme substrate. L-Lactaldehyde is oxidized to L-lactate by NAD-dependent lactaldehyde dehydrogenase. L-Lactaldehyde is reduced to L-1,2-propanediol by NADH/NADPH-dependent oxidoreductases. L-Lactaldehyde is used in studies of microbial sugar metabolism and carbonyl metabolism.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3913-64-2
- 分子式: C3H6O2
- 分子量:74.08
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
More
生物活性
Purified dog liver dimeric dihydrodiol dehydrogenase reduces L-Lactaldehyde ((2S)-Hydroxypropanal), with a Km value of 0.67 mM, a Vmax value of 1.15 units/mg, and a Vmax/Km ratio of 1.7 units/mg/mM[1].
L-Lactaldehyde is an NADH-dependent substrate of Escherichia coli propanediol oxidoreductase, which can be reduced to L-1,2-propanediol. Its Km is 0.035 mM, Vmax is 20 μmol/min/mg, and the optimal pH for the reaction is 6.5[2].
L-Lactaldehyde acts as a stereoselective substrate for Saccharomyces cerevisiae NAD-dependent lactaldehyde dehydrogenase, which oxidizes it to L-lactate with a Km of 10 mM, whereas the activity of D-lactaldehyde is only 0.2% that of L-Lactaldehyde[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 3913-64-2
-
分子量 74.08
-
分子式 C3H6O2
-
SMILES
O=C[C@@H](O)C
-
別名
(2S)-Hydroxypropanal
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Sato K, et al. Purification and characterization of dimeric dihydrodiol dehydrogenase from dog liver. Journal of biochemistry. 1994 Sep;116(3):711-7. [Content Brief]
[2]. Boronat A, et al. Rhamnose-induced propanediol oxidoreductase in Escherichia coli: purification, properties, and comparison with the fucose-induced enzyme. Journal of bacteriology. 1979 Nov;140(2):320-6. [Content Brief]
[3]. Inoue Y, et al. Metabolism of 2-oxoaldehydes in yeasts. Purification and characterization of lactaldehyde dehydrogenase from Saccharomyces cerevisiae. European journal of biochemistry. 1985 Dec 02;153(2):243-7. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
L-Lactaldehyde 関連分類
HY-184860 関連分類
Powered by Bioz
- L-Lactaldehyde
- 3913-64-2
- (2S)-Hydroxypropanal
- Endogenous Metabolite
- Saccharomyces cerevisiae
- lactaldehyde dehydrogenase
- dehydrogenases
- methylglyoxal reductase
- Escherichia coli K-12 strain 1
- Escherichia coli
- L-specific oxidoreductases
- dihydrodiol dehydrogenase
- propanediol oxidoreductase
- L-lactate
- Inhibitor
- inhibitor
- inhibit