m-PEG1-NHS ester
Based on 1 Customer Validation
m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 95.0%
- CAS 番号: 1027371-75-0
- 分子式: C8H11NO5
- 分子量:201.18
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-124323
m-PEG4-NHS esterPROTAC Linkers -
HY-133066
m-PEG6-NHS esterPROTAC Linker -
HY-133065
m-PEG5-NHS esterPROTAC Linkers -
HY-130446
m-PEG9-NHS ester -
HY-W019793
m-PEG8-NHS ester -
HY-133064
m-PEG3-NHS esterPROTAC Linkers -
HY-141106
m-PEG12-NHS esterPROTAC Linkers -
HY-W190842
m-PEG2-NHS esterBiochemical Assay Reagents -
HY-122413
m-PEG7-NHS esterPROTAC Linkers
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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PEGs |
Alkyl/ether |
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 1027371-75-0
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性状 Solid
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分子量 201.18
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分子式 C8H11NO5
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Color White to light yellow
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SMILES
COCCC(ON1C(CCC1=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
H2O : 33.33 mg/mL (165.67 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
体内:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (497.07 mM); Clear solution; Need ultrasonic
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.9707 mL | 24.8534 mL | 49.7067 mL | 124.2668 mL |
| 5 mM | 0.9941 mL | 4.9707 mL | 9.9413 mL | 24.8534 mL | |
| 10 mM | 0.4971 mL | 2.4853 mL | 4.9707 mL | 12.4267 mL | |
| 15 mM | 0.3314 mL | 1.6569 mL | 3.3138 mL | 8.2845 mL | |
| 20 mM | 0.2485 mL | 1.2427 mL | 2.4853 mL | 6.2133 mL | |
| 25 mM | 0.1988 mL | 0.9941 mL | 1.9883 mL | 4.9707 mL | |
| 30 mM | 0.1657 mL | 0.8284 mL | 1.6569 mL | 4.1422 mL | |
| 40 mM | 0.1243 mL | 0.6213 mL | 1.2427 mL | 3.1067 mL | |
| 50 mM | 0.0994 mL | 0.4971 mL | 0.9941 mL | 2.4853 mL | |
| 60 mM | 0.0828 mL | 0.4142 mL | 0.8284 mL | 2.0711 mL | |
| 80 mM | 0.0621 mL | 0.3107 mL | 0.6213 mL | 1.5533 mL | |
| 100 mM | 0.0497 mL | 0.2485 mL | 0.4971 mL | 1.2427 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
m-PEG1-NHS ester 関連分類
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