Mal-PEG2-NHS ester
Based on 1 Customer Validation
Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.55%
- CAS 番号: 1433997-01-3
- 分子式: C15H18N2O8
- 分子量:354.31
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
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Non-cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1433997-01-3
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性状 Viscous Liquid
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分子量 354.31
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分子式 C15H18N2O8
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Color Colorless to off-white
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SMILES
O=C(ON1C(CCC1=O)=O)CCOCCOCCN2C(C=CC2=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (282.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 6.67 mg/mL (18.83 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (242 KB)
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SDS (394 KB)
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- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.8224 mL | 14.1119 mL | 28.2239 mL | 70.5597 mL |
| 5 mM | 0.5645 mL | 2.8224 mL | 5.6448 mL | 14.1119 mL | |
| 10 mM | 0.2822 mL | 1.4112 mL | 2.8224 mL | 7.0560 mL | |
| 15 mM | 0.1882 mL | 0.9408 mL | 1.8816 mL | 4.7040 mL | |
| DMSO | 20 mM | 0.1411 mL | 0.7056 mL | 1.4112 mL | 3.5280 mL |
| 25 mM | 0.1129 mL | 0.5645 mL | 1.1290 mL | 2.8224 mL | |
| 30 mM | 0.0941 mL | 0.4704 mL | 0.9408 mL | 2.3520 mL | |
| 40 mM | 0.0706 mL | 0.3528 mL | 0.7056 mL | 1.7640 mL | |
| 50 mM | 0.0564 mL | 0.2822 mL | 0.5645 mL | 1.4112 mL | |
| 60 mM | 0.0470 mL | 0.2352 mL | 0.4704 mL | 1.1760 mL | |
| 80 mM | 0.0353 mL | 0.1764 mL | 0.3528 mL | 0.8820 mL | |
| 100 mM | 0.0282 mL | 0.1411 mL | 0.2822 mL | 0.7056 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.