ME3221

ME3221 is an angiotensin AT1 receptor antagonist that effectively antagonizes the pressor response to angiotensin II in rats and marmosets without affecting the hypotensive response to bradykinin. It demonstrates potent antihypertensive effects in renal hypertensive rats and spontaneously hypertensive rats (SHR). ME3221's repeated administration in SHR results in sustained and stable hypotensive effects without affecting heart rate, indicating its potential for studying both renal and essential hypertension.

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  • CAS 番号: 139958-16-0
  • 分子式: C22H21N5O2
  • 分子量:387.43
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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