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MerTK-IN-2

MerTK-IN-2 (compound 15f) is an orally active MerTK inhibitor with an IC50 of 37.5 nM. MerTK-IN-2 can induce apoptosis. MerTK-IN-2 has antitumor activity with IC50 values of 1.79, 18.32, and 2.18 μM for human ovarian cancer cells A2780, breast cancer cells MDA-MB-231, and colon cancer cells HCT116, respectively.

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  • 分子式: C22H21FN6O
  • 分子量:404.44
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • MerTK-IN-2 Chemical Structure
    MerTK-IN-2 構造式
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  • MerTK-IN-2 Chemical Structure
    MerTK-IN-2 Chemical Structure
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  • MerTK-IN-2