Metribuzin
Based on 1 Customer Validation
Metribuzin is a low-cost non-selective herbicide belonging to the chemical class of triazinones. Metribuzin inhibits plant DNA synthesis and acts on photosystem II, ultimately suppressing photosynthesis. Metribuzin provides excellent control of important annual grass and broadleaf weeds.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.91%
- CAS 番号: 21087-64-9
- 分子式: C8H14N4OS
- 分子量:214.29
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
製品説明
体外実験
Metribuzin inhibits photosystem II electron transport in plant chloroplasts, exerting herbicidal effects[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
Metribuzin (6.44 mg/kg) disrupts glomerular function in pregnant rabbits[2].
Metribuzin (single dose; p.o.) has an acute oral LD50 of 1090 mg/kg in rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rats[2]
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Dosage:single dose (LD50 determination)
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Administration:p.o.
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Result:Reached an oral LD50 of 1090 mg/kg.
化学情報
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CAS 番号 21087-64-9
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性状 Solid
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分子量 214.29
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分子式 C8H14N4OS
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Color White to off-white
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SMILES
O=C1N(C(SC)=NN=C1C(C)(C)C)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 87.5 mg/mL (408.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
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データシート (274 KB)
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SDS (596 KB)
- English - EN (596 KB)
- Français - FR (596 KB)
- Deutsch - DE (596 KB)
- Norwegian - NO (596 KB)
- Español - ES (596 KB)
- Swedish - SV (596 KB)
- Italian - IT (596 KB)
- Korean - KR (596 KB)
- Portuguese - PT (596 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6666 mL | 23.3329 mL | 46.6657 mL | 116.6643 mL |
| 5 mM | 0.9333 mL | 4.6666 mL | 9.3331 mL | 23.3329 mL | |
| 10 mM | 0.4667 mL | 2.3333 mL | 4.6666 mL | 11.6664 mL | |
| 15 mM | 0.3111 mL | 1.5555 mL | 3.1110 mL | 7.7776 mL | |
| 20 mM | 0.2333 mL | 1.1666 mL | 2.3333 mL | 5.8332 mL | |
| 25 mM | 0.1867 mL | 0.9333 mL | 1.8666 mL | 4.6666 mL | |
| 30 mM | 0.1556 mL | 0.7778 mL | 1.5555 mL | 3.8888 mL | |
| 40 mM | 0.1167 mL | 0.5833 mL | 1.1666 mL | 2.9166 mL | |
| 50 mM | 0.0933 mL | 0.4667 mL | 0.9333 mL | 2.3333 mL | |
| 60 mM | 0.0778 mL | 0.3889 mL | 0.7778 mL | 1.9444 mL | |
| 80 mM | 0.0583 mL | 0.2917 mL | 0.5833 mL | 1.4583 mL | |
| 100 mM | 0.0467 mL | 0.2333 mL | 0.4667 mL | 1.1666 mL |