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United States

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製品番号: HY-N21574

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Milliamine D

Milliamine D is a diterpenoid toxin of the ingenol ester class containing an anthraniloyl tripeptide, existing in the free base form and exhibiting molluscicidal activity. Milliamine D can be used in the study of schistosomiasis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 88524-59-8
分子式: C₄₅H₄₉N₃O₁₀
分子量:791.88

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Milliamine D 構造式

CAS 番号: 88524-59-8

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Parasite アイソフォーム固有の製品をすべて表示 :

体外実験

Bacterial InfectionOthers

Bacterial Infection

Milliamine D (compound 7) (100 μg/L; 24 h) kills 100% of Biomphalaria glabrata snails^[2].

Others

Milliamine D is a 5,20-diester of ingenol, featuring an anthraniloyl tripeptide side chain with a terminal N,N-dimethylamino group and an acetyl group at position 20^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Milliamine D (0.18 nmol; topical application; single administration) induces ear irritation in mice, with an ID₅₀²⁴of 0.18 nmol^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

NMRI (ear irritation assay; tumour promotion tests strain)^[1]
Dosage:

0.18 nmol
Administration:

topical; single application
Result:

Was determined to have a 24-hour irritant dose 50 of 0.18 nmol for ear irritation.
Exhibited an irritancy (I²⁴ = 1/ID₅₀²⁴) of 5.6 nmol^-1.

化学情報

CAS 番号 88524-59-8
分子量 791.88
分子式 C₄₅H₄₉N₃O₁₀
SMILES

O=C(O[C@@H]1C(COC(C)=O)=C[C@](C2=O)([H])[C@@]3([H])[C@@](C3(C)C)([H])C[C@@H](C)[C@@]42[C@]1(O)[C@@H](O)C(C)=C4)C5=CC=CC=C5NC(C6=CC=CC(O)=C6NC(C7=CC=CC=C7N(C)C)=O)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Marston A, et al. On the Active Principles of the Euphorbiaceae VI: Isolation and Biological Activities of Seven Milliamines from Euphorbia milii. Planta Med,1983,47(3):141-147.

[2]. Carlos Leomar Zani, et al. Molluscicidal milliamines from Euphorbia milii var. hislopii, Phytochemistry,
Volume 34, Issue 1, 1993, Pages 89-95, ISSN 0031-9422.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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