N3-PEG5-aldehyde
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2566404-73-5
- 分子式: C20H30N4O7
- 分子量:438.47
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2566404-73-5
-
分子量 438.47
-
分子式 C20H30N4O7
-
SMILES
[H]C(C(C=C1)=CC=C1C(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)