Odoroside A
Based on 1 Customer Validation
Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. Odoroside A has anti-cancer activity. Odoroside A could induce apoptosis and cell cycle arrest through ROS/p53 signaling pathway, leading to the tumor cell death.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.73%
- CAS 番号: 12738-19-1
- 分子式: C30H46O7
- 分子量:518.68
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>316 μM
Compound: 6
|
Viability of human A549 cells by MTT assay after 24 hrs
Viability of human A549 cells by MTT assay after 24 hrs
|
[PMID: 17595134] |
| A549 | IC50 |
0.2 μM
Compound: 6
|
Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr
Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr
|
[PMID: 17595134] |
| A549 | IC50 |
0.48 μM
Compound: 6
|
Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr
Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr
|
[PMID: 17595134] |
| HepG2 | IC50 |
1.5 mM
Compound: 6
|
Growth inhibition of human HepG2 cells
Growth inhibition of human HepG2 cells
|
[PMID: 17595134] |
| WI-38 | IC50 |
0.07 mM
Compound: 6
|
Growth inhibition of human WI38 cells
Growth inhibition of human WI38 cells
|
[PMID: 17595134] |
| WI-38 VA13 | IC50 |
0.18 mM
Compound: 6
|
Growth inhibition of human VA13 cells
Growth inhibition of human VA13 cells
|
[PMID: 17595134] |
化学情報
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CAS 番号 12738-19-1
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性状 Solid
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分子量 518.68
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分子式 C30H46O7
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Color White to off-white
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SMILES
O[C@@]([C@@]1(CC2)C)(CC[C@]1([H])C(CO3)=CC3=O)[C@@](CC[C@]4([H])C[C@H]5O[C@H](O[C@@H]6C)C[C@H]([C@H]6O)OC)([H])[C@@]2([H])[C@]4(CC5)C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : 100 mg/mL (192.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9280 mL | 9.6399 mL | 19.2797 mL | 48.1993 mL |
| 5 mM | 0.3856 mL | 1.9280 mL | 3.8559 mL | 9.6399 mL | |
| 10 mM | 0.1928 mL | 0.9640 mL | 1.9280 mL | 4.8199 mL | |
| 15 mM | 0.1285 mL | 0.6427 mL | 1.2853 mL | 3.2133 mL | |
| 20 mM | 0.0964 mL | 0.4820 mL | 0.9640 mL | 2.4100 mL | |
| 25 mM | 0.0771 mL | 0.3856 mL | 0.7712 mL | 1.9280 mL | |
| 30 mM | 0.0643 mL | 0.3213 mL | 0.6427 mL | 1.6066 mL | |
| 40 mM | 0.0482 mL | 0.2410 mL | 0.4820 mL | 1.2050 mL | |
| 50 mM | 0.0386 mL | 0.1928 mL | 0.3856 mL | 0.9640 mL | |
| 60 mM | 0.0321 mL | 0.1607 mL | 0.3213 mL | 0.8033 mL | |
| 80 mM | 0.0241 mL | 0.1205 mL | 0.2410 mL | 0.6025 mL | |
| 100 mM | 0.0193 mL | 0.0964 mL | 0.1928 mL | 0.4820 mL |