OXFBD03
OXFBD03 serves as an inhibitor of the BRD4(1) protein, which belongs to the bromodomain and extra terminal domain bromodomain family.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1429129-71-4
- 分子式: C20H19NO4
- 分子量:337.37
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 9
|
Cytotoxicity against human A549 cells after 72 hrs by MTS assay
Cytotoxicity against human A549 cells after 72 hrs by MTS assay
|
[PMID: 23517011] |
| HeLa | IC50 |
>100 μM
Compound: 9
|
Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
|
[PMID: 23517011] |
| MV4-11 | IC50 |
0.616 μM
Compound: 9
|
Cytotoxicity against human MV4-11 cells after 72 hrs by MTS assay
Cytotoxicity against human MV4-11 cells after 72 hrs by MTS assay
|
[PMID: 23517011] |
| NCI-H1975 | IC50 |
>10 μM
Compound: 9
|
Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTS assay
Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTS assay
|
[PMID: 23517011] |
| U2OS | IC50 |
>100 μM
Compound: 9
|
Cytotoxicity against human U2OS cells after 24 hrs by WST-1 assay
Cytotoxicity against human U2OS cells after 24 hrs by WST-1 assay
|
[PMID: 23517011] |
化学情報
-
CAS 番号 1429129-71-4
-
分子量 337.37
-
分子式 C20H19NO4
-
SMILES
OC(C1=CC=CC=C1)C2=CC(C3=C(C)ON=C3C)=CC(OC(C)=O)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)