P-gp modulator 3
P-gp modulator 3 (Compound 37) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator.
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- CAS 番号: 2987145-15-1
- 分子式: C31H36N2O6
- 分子量:532.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L5178Y | IC50 |
>=11.3 μM
Compound: 37
|
Cytotoxicity against multi-drug resistant mouse L5178Y cells transfected with ABCB1 gene assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against multi-drug resistant mouse L5178Y cells transfected with ABCB1 gene assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
|
[PMID: 33038666] |
| L5178Y | IC50 |
>=11.3 μM
Compound: 37
|
Cytotoxicity against parental mouse L5178Y cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against parental mouse L5178Y cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
|
[PMID: 33038666] |
化学情報
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CAS 番号 2987145-15-1
-
分子量 532.63
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分子式 C31H36N2O6
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SMILES
COC1=CC2=C(C(O)=C1)C(C[C@H](O2)C3=CC=C(C=C3)OCC(CNC4CCN(CC4)CC5=CC=CC=C5)O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)