PAM 1392
PAM 1392 is active orally against Plasmodium berghei in mice, P. cynofologi and P. knowlesi in monkeys and Trypanosoma cruzi in tissue cultures of mice, and hemolytic streptococci in vitro. PAM 1392 has antimalarial and antitrypanosomal activities, which is proming for rasearch of drug-resistant malaria.
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- CAS 番号: 13794-65-5
- 分子式: C15H13Cl2N5
- 分子量:334.20
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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生物活性
化学情報
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CAS 番号 13794-65-5
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分子量 334.20
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分子式 C15H13Cl2N5
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SMILES
NC1=NC(N)=C2C=C(NCC3=CC=C(Cl)C(Cl)=C3)C=CC2=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Shepard CC. Further experience with the kinetic method for the study of drugs against Mycobacterium leprae in mice. Activities of DDS, DFD, ethionamide, capreomycin and PAM 1392. Int J Lepr Other Mycobact Dis. 1969 Oct-Dec;37(4):389-97. [Content Brief]
[2]. Thompson PE, et al. PAM 1392 (2,4-diamino-6-(3,4-dichlorobenzylamino) quinazoline) as a chemotherapeutic agent: Plasmodium berghei, P. cynomolgi, P. Exp Parasitol. 1969 Aug;25(1):32-49. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PAM 1392 関連分類
HY-124112 関連分類
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