パーフルオロデカリン
Based on 1 Customer Validation
Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood. Perfluorodecalin enhances bone regeneration and cell viability.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 306-94-5
- 分子式: C10F18
- 分子量:462.08
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Perfluorodecalin prolongs the cells survival in anaerobic environment, enhances the radiopacity, injectability, cohesion of bone cements and the bone regeneration[4]. Perfluorodecalin (10% v/v) ameliorates hypoxia and increases cell viability in transplantation of encapsulated islets[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Albino rabbits[2]
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Dosage:1.1-1.5 ml for each eye
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Administration:injection into vitreous cavity
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Result:Induced appearance of foam cells, preretinal membranes, and the interface necrosis.
化学情報
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CAS 番号 306-94-5
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性状 Liquid (Density: 1.9456 g/cm3)
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分子量 462.08
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分子式 C10F18
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Color Colorless to light yellow
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SMILES
FC12C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)C(F)(F)C(F)(F)C(F)(F)C2(F)F
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別名
Perfluorodecalin; PP 5; Perfluorodecahydronaphthalene
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 66.67 mg/mL (144.28 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (466 KB)
- English - EN (466 KB)
- Français - FR (466 KB)
- Deutsch - DE (466 KB)
- Norwegian - NO (466 KB)
- Español - ES (466 KB)
- Swedish - SV (466 KB)
- Italian - IT (466 KB)
- Korean - KR (466 KB)
- Portuguese - PT (466 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Orzalesi N, et al. Experimental short-term tolerance to perfluorodecalin in the rabbit eye: a histopathological study. Curr Eye Res. 1998;17(8):828-835. [Content Brief]
[2]. Bourke RD, et al. Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin. Am J Ophthalmol. 1994;118(3):403-404. [Content Brief]
[3]. Spahn DR. Blood substitutes. Artificial oxygen carriers: perfluorocarbon emulsions. Crit Care. 1999;3(5):R93-7. [Content Brief]
[4]. Tamimi F, et al., Perfluorodecalin and bone regeneration. Eur Cell Mater. 2013 Jan 2;25:22-36. [Content Brief]
[5]. Rodriguez-Brotons A, et al., Comparison of Perfluorodecalin and HEMOXCell as Oxygen Carriers for Islet Oxygenation in an In Vitro Model of Encapsulation. Tissue Eng Part A. 2016 Dec;22(23-24):1327-1336. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1641 mL | 10.8206 mL | 21.6413 mL | 54.1032 mL |
| 5 mM | 0.4328 mL | 2.1641 mL | 4.3283 mL | 10.8206 mL | |
| 10 mM | 0.2164 mL | 1.0821 mL | 2.1641 mL | 5.4103 mL | |
| 15 mM | 0.1443 mL | 0.7214 mL | 1.4428 mL | 3.6069 mL | |
| 20 mM | 0.1082 mL | 0.5410 mL | 1.0821 mL | 2.7052 mL | |
| 25 mM | 0.0866 mL | 0.4328 mL | 0.8657 mL | 2.1641 mL | |
| 30 mM | 0.0721 mL | 0.3607 mL | 0.7214 mL | 1.8034 mL | |
| 40 mM | 0.0541 mL | 0.2705 mL | 0.5410 mL | 1.3526 mL | |
| 50 mM | 0.0433 mL | 0.2164 mL | 0.4328 mL | 1.0821 mL | |
| 60 mM | 0.0361 mL | 0.1803 mL | 0.3607 mL | 0.9017 mL | |
| 80 mM | 0.0271 mL | 0.1353 mL | 0.2705 mL | 0.6763 mL | |
| 100 mM | 0.0216 mL | 0.1082 mL | 0.2164 mL | 0.5410 mL |
Perfluorodecalin 関連分類
HY-108298 関連分類
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