Phenolic acid
Phenolic acid is an endogenous metabolite.
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- CAS 番号: 29656-58-4
- 分子式: C7H8D2O3
- 分子量:144.16
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | IC50 |
5 mM
Compound: salicylic acid
|
Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay
Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay
|
[PMID: 26617961] |
| DU-145 | IC50 |
>100 μM
Compound: 2; Salic
|
Antiproliferative activity against human DU-145 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human DU-145 cells incubated for 48 hrs by MTT assay
|
[PMID: 36257283] |
| HEK293 | IC50 |
>15 mM
Compound: Salicylate
|
Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay
Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay
|
[PMID: 28341401] |
| HT-29 | IC50 |
>100 μM
Compound: 2; Salic
|
Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
|
[PMID: 36257283] |
| MCF7 | IC50 |
>100 μM
Compound: 2; Salic
|
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
|
[PMID: 36257283] |
| RAW264.7 | CC50 |
>40 μM
Compound: 1
|
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in survival rate after 24 hrs by MTT assay
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in survival rate after 24 hrs by MTT assay
|
[PMID: 25200306] |
| Sf9 | IC50 |
500 μM
Compound: salicylic acid
|
Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5 mins by HTRF assay
Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5 mins by HTRF assay
|
[PMID: 27046190] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 29656-58-4
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分子量 144.16
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分子式 C7H8D2O3
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SMILES
OC([2H])=O.[D1]O[H].C1=CC=CC=C1
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)