(+)-Hannokinol
(+)-Hannokinol can be isolated from AMOMUM TSAO-KO (ginger family) fruit. (+)-Hannokinol inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 408324-76-5
- 分子式: C19H24O4
- 分子量:316.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
>10 μM
Compound: 9
|
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
|
[PMID: 23910596] |
| HL-60 | IC50 |
>10 μg/mL
Compound: 9a
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 11908966] |
| HSC-2 | IC50 |
231 μg/mL
Compound: 9a
|
Cytotoxicity against human HSC2 cells by MTT assay
Cytotoxicity against human HSC2 cells by MTT assay
|
[PMID: 11908966] |
| RAW264.7 | IC50 |
>100 μM
Compound: 7a
|
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
|
[PMID: 21807513] |
化学情報
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CAS 番号 408324-76-5
-
分子量 316.39
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分子式 C19H24O4
-
SMILES
OC(C=C1)=CC=C1CC[C@@H](O)C[C@H](O)CCC2=CC=C(C=C2)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (263 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)