Pro-xylane (30% in water)
Based on 1 publication(s) in Google Scholar
Pro-xylane (30% in water) (Hydroxypropyl tetrahydropyrantriol) is a bioactive C-glycoside that targets the biosynthesis pathway of glycosaminoglycans/mucopolysaccharides (GAGs) in the skin matrix and can be absorbed transdermally. Pro-xylane (30% in water) stimulates the biosynthesis of GAGs in fibroblasts, enhances the structural stability of the skin extracellular matrix, improves skin elasticity and moisturizing ability, and delays wrinkle formation. Pro-xylane (30% in water) can effectively promote the synthesis of collagen fibers and hyaluronic acid in the dermis. Pro-xylane (30% in water) is used in the field of anti-aging cosmetics to improve skin hydration and elasticity. Pro-xylane (30% in water) is eco-friendly and biodegradable.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 439685-79-7
- 分子式: C8H16O5
- 分子量:192.21
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保管条件:
Solution, -20°C, 2 years
MedChemExpress(MCE)の使用を引用している文献 Pro-xylane (30% in water)
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生物活性
Pro-xylane (30% in water) (0.3-3.0 mM; 96 h) stimulates the synthesis of GAGs in human fibroblasts[1].
Pro-xylane (30% in water) is the catalytic substrate of the recombinant carbonyl reductase R129E/D210F, whose key activity lies in the high stereoselectivity of the β-S configuration. Under the catalysis of R129E/D210F, Pro-xylane (30% in water) produces >99% β,S-diastereomeric excess[2].
Pro-xylane (30% in water) has the ability of efficient asymmetric synthesis[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 439685-79-7
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性状 Liquid
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分子量 192.21
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分子式 C8H16O5
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Color Colorless to light yellow
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SMILES
CC(O)C[C@H]1[C@@H]([C@H]([C@H](O)CO1)O)O
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別名
Hydroxypropyl tetrahydropyrantriol (30% in water)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Solution, -20°C, 2 years
Publications (1)
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Journal Impact Factor
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Most Recent
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Mech Ageing Dev
Pro-Xylane alleviates ultraviolet-induced skin senescence through SGK1-mediated p21 ubiquitination and subcellular translocation. [Abstract]2026 Aug:232:112194. PMID: 42155870
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Cavezza A, et al. Synthesis of Pro-Xylane: a new biologically active C-glycoside in aqueous media. Bioorg Med Chem Lett. 2009 Feb 1;19(3):845-9. [Content Brief]
[2]. Dou Z, et al. Extensive gene mining and facile engineering of a novel carbonyl reductase for asymmetric synthesis of anti-aging (S)-Pro-Xylane from d-xylose. Int J Biol Macromol. 2025 May;305(Pt 2):140976. [Content Brief]
[3]. Zhao Y, et al. Engineering a Carbonyl Reductase for High-Efficiency Synthesis of Optically Pure (S)-Pro-Xylane: An Alternative Synthetic Route. J Agric Food Chem. 2025 Apr 23;73(16):9759-9768. [Content Brief]
[4]. Wu B, et al. Liposomal gel loaded with pro-xylane intermediate promotes chronic wound healing. Pak J Pharm Sci. 2024 Jul;37(4):723-730. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)