Refinicopan
Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits hemolysis of rabbit red blood cells. Refinicopan can be used to study diseases mediated by complement factor D.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2922808-66-8
- 分子式: C29H32N2O3
- 分子量:456.58
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Complement factor D 10 nM (IC50) |
Refinicopan (Compound 001) inhibits hemolysis of rabbit red blood cells in a cell-based assay with an IC50 of 41 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2922808-66-8
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分子量 456.58
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分子式 C29H32N2O3
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SMILES
NCC1=CC=CC(C2=CC(N3CCC4(CC3)CC4)=CC(COC5=C(C=CC=C5)CC(O)=O)=C2)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)