RPR103611
RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC50s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 150840-75-8
- 分子式: C46H78N2O6
- 分子量:755.12
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9 | EC50 |
0.03 μM
Compound: 12
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Toxic concentration on HIV-1 mock infected H9 lymphocyte cells
Toxic concentration on HIV-1 mock infected H9 lymphocyte cells
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[PMID: 8676334] |
| H9 | IC50 |
2.7 μM
Compound: 12
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Inhibitory activity against HIV-1 replication in mock infected H9 cells
Inhibitory activity against HIV-1 replication in mock infected H9 cells
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[PMID: 8676334] |
| TZM | CC50 |
17 μM
Compound: 2; RPR103611
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Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTitre-Glo assay
Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTitre-Glo assay
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[PMID: 35513221] |
化学情報
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CAS 番号 150840-75-8
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分子量 755.12
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分子式 C46H78N2O6
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SMILES
[H][C@@]12CC[C@@]3([C@](CC[C@@]4([C@]5([C@@H](CC[C@@]5(CC[C@]43C)C(NCCCCCCCC(N[C@H]([C@H](CC(O)=O)O)CC(C)C)=O)=O)C(C)=C)[H])[H])([C@]1(CC[C@@H](C2(C)C)O)C)[H])C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
RPR103611 関連分類
HY-146338 関連分類
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