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製品番号: HY-16172A

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(S)-DMAPT

Name: (S)-DMAPT
Brand: MedChemExpress
SKU: HY-16172A
Price: 121.00 USD
Availability: PreOrder

(別名: (S)-Dimethylamino Parthenolide)

(S)-DMAPT ((S)-Dimethylamino Parthenolide) is a sesquiterpene lactone with radioprotective and radiation-mitigating effects. (S)-DMAPT alleviates radiation-induced bladder fibrosis and fibrosis markers in the lungs and bladder. (S)-DMAPT alleviates radiation-induced oligospermia, colorectal tissue senescence, and testicular senescence. (S)-DMAPT prevents radiation-induced skin damage.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 870677-05-7
分子式: C₁₇H₂₇NO₃
分子量:293.40

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

(S)-DMAPT 構造式

CAS 番号: 870677-05-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体内実験

(S)-DMAPT limits early radiation-induced bladder fibrosis after LD50 whole-body irradiation in mice^[1].
(S)-DMAPT (thrice weekly every week; from one week pre-irradiation to study endpoint) reduces radiation-induced SA-β-Gal senescence in colorectal tissue and testis of C57BL/6J mice^[1].
(S)-DMAPT (on the day of irradiation; once a day for the subsequent three days) reduces lung and bladder RNA expression of the ARS/fibrosis biomarkers Wnt3 and Ddb2 after high-dose whole-body irradiation in C57BL/6J mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 870677-05-7
分子量 293.40
分子式 C₁₇H₂₇NO₃
SMILES

C[C@]12[C@@](O2)([H])[C@]3([H])[C@](CC/C(C)=C\CC1)([H])[C@H](C(O3)=O)CN(C)C
別名

(S)-Dimethylamino Parthenolide
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (277 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Christopher Sweeney, et al. Methods of minimising effects of radiation exposure. WO2025065057A1.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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