SR-4554
Based on 1 Customer Validation
SR-4554 is a probe for the measurement of tumor hypoxia. SR-4554 undergoes enzymatic single-electron reduction reactions within hypoxic cells. SR-4554 determines the 19F retention index for four commonly used mouse tumors (EMT6, SCCVII, KILT and RIF-I) through 19F MRS technique. SR-4554 can used to detect tumor Hypoxia noninvasively by 19F magnetic resonance spectroscopy (19F MRS).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.60%
- CAS 番号: 167648-73-9
- 分子式: C8H9F3N4O4
- 分子量:282.18
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
| Species | Dose | Route | Tmax | T1/2 | Clearance (CL) | Vd | AUC0-∞ |
|---|---|---|---|---|---|---|---|
| Mice[1] | 180 mg/kg | i.p. | 45 min | 51 min | 29 mL/min/kg | 1.8 L/kg | 0.36 μM·h |
化学情報
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CAS 番号 167648-73-9
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性状 Solid
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分子量 282.18
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分子式 C8H9F3N4O4
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Color White to off-white
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SMILES
O=C(NCC(O)C(F)(F)F)CN1C=CN=C1[N+]([O-])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (354.38 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5438 mL | 17.7192 mL | 35.4384 mL | 88.5959 mL |
| 5 mM | 0.7088 mL | 3.5438 mL | 7.0877 mL | 17.7192 mL | |
| 10 mM | 0.3544 mL | 1.7719 mL | 3.5438 mL | 8.8596 mL | |
| 15 mM | 0.2363 mL | 1.1813 mL | 2.3626 mL | 5.9064 mL | |
| 20 mM | 0.1772 mL | 0.8860 mL | 1.7719 mL | 4.4298 mL | |
| 25 mM | 0.1418 mL | 0.7088 mL | 1.4175 mL | 3.5438 mL | |
| 30 mM | 0.1181 mL | 0.5906 mL | 1.1813 mL | 2.9532 mL | |
| 40 mM | 0.0886 mL | 0.4430 mL | 0.8860 mL | 2.2149 mL | |
| 50 mM | 0.0709 mL | 0.3544 mL | 0.7088 mL | 1.7719 mL | |
| 60 mM | 0.0591 mL | 0.2953 mL | 0.5906 mL | 1.4766 mL | |
| 80 mM | 0.0443 mL | 0.2215 mL | 0.4430 mL | 1.1074 mL | |
| 100 mM | 0.0354 mL | 0.1772 mL | 0.3544 mL | 0.8860 mL |
SR-4554 関連分類
HY-116156 関連分類
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