TB-21007
Based on 1 Customer Validation
TB-21007 is a selective and brain penetrant α5 subunit-containing GABAA receptor inverse agonist with Kis of 1.6 nM, 20 nM, 16 nM, and 20 nM for α5, α1, α2 and α3 subtypes, respectively. TB-21007 enhances cognition in rats.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.7%
- CAS 番号: 207306-50-1
- 分子式: C15H17NO2S3
- 分子量:339.50
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Male hooded Lister rats were trained in the water maze task[1]
-
Dosage:0.3 mg/kg
-
Administration:ip; for 5 days
-
Result:Significantly enhanced performance in this hippocampal-dependent memory task.
化学情報
-
CAS 番号 207306-50-1
-
性状 Solid
-
分子量 339.50
-
分子式 C15H17NO2S3
-
Color Off-white to light yellow
-
SMILES
O=C1CC(C)(C)CC2=C(C3=NC=CS3)SC(SCCO)=C21
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 40 mg/mL (117.82 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (275 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9455 mL | 14.7275 mL | 29.4551 mL | 73.6377 mL |
| 5 mM | 0.5891 mL | 2.9455 mL | 5.8910 mL | 14.7275 mL | |
| 10 mM | 0.2946 mL | 1.4728 mL | 2.9455 mL | 7.3638 mL | |
| 15 mM | 0.1964 mL | 0.9818 mL | 1.9637 mL | 4.9092 mL | |
| 20 mM | 0.1473 mL | 0.7364 mL | 1.4728 mL | 3.6819 mL | |
| 25 mM | 0.1178 mL | 0.5891 mL | 1.1782 mL | 2.9455 mL | |
| 30 mM | 0.0982 mL | 0.4909 mL | 0.9818 mL | 2.4546 mL | |
| 40 mM | 0.0736 mL | 0.3682 mL | 0.7364 mL | 1.8409 mL | |
| 50 mM | 0.0589 mL | 0.2946 mL | 0.5891 mL | 1.4728 mL | |
| 60 mM | 0.0491 mL | 0.2455 mL | 0.4909 mL | 1.2273 mL | |
| 80 mM | 0.0368 mL | 0.1841 mL | 0.3682 mL | 0.9205 mL | |
| 100 mM | 0.0295 mL | 0.1473 mL | 0.2946 mL | 0.7364 mL |
TB-21007 関連分類
HY-103510 関連分類
Powered by Bioz