Terrestribisamide
Terrestribisamide ((E)-N,N′-Diferuloylputrescine) can be isolated from dried fruits of Tribulus terrestris. Terrestribisamide has antibacterial, antifungal, antioxidant, anticancer effects.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 91000-13-4
- 分子式: C24H28N2O6
- 分子量:440.49
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| B16-F1 | IC50 |
>150 μM
Compound: 12
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Antimelanogenic activity in mouse B16-F1 cells assessed as reduction in alpha-MSH-stimulated melanin production preincubated for 72 hrs followed by alpha-MSH-stimulation and measured after 2 hrs
Antimelanogenic activity in mouse B16-F1 cells assessed as reduction in alpha-MSH-stimulated melanin production preincubated for 72 hrs followed by alpha-MSH-stimulation and measured after 2 hrs
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[PMID: 30446440] |
| B16-F1 | IC50 |
88.4 μM
Compound: 12
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Inhibition of tyrosinase in mouse B16-F1 cells
Inhibition of tyrosinase in mouse B16-F1 cells
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[PMID: 30446440] |
| COLO 320 | IC50 |
50 μg/mL
Compound: 1
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Cytotoxicity against Homo sapiens (human) COLO320 cells by MTT assay
Cytotoxicity against Homo sapiens (human) COLO320 cells by MTT assay
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10.1007/s00044-012-0393-3 |
化学情報
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CAS 番号 91000-13-4
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分子量 440.49
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分子式 C24H28N2O6
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SMILES
COC(C=C1/C=C/C(NCCCCNC(/C=C/C2=CC(OC)=C(C=C2)O)=O)=O)=C(C=C1)O
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別名
(E)-N,N′-Diferuloylputrescine
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Terrestribisamide 関連分類
HY-N12267A 関連分類
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