Timigutuzumab
Based on 1 Customer Validation
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody that targets ErbB2. Timigutuzumab can be used for the research of cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.53%
- CAS 番号: 1665274-14-5
- 分子量:145.32 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
Human IgG1 kappa
Human
ERBB2/HER2/CD340
Timigutuzumab is glyco-optimized to enhance antibody-dependent cell-mediated cytotoxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG1 kappa
ELISA, FACS, Functional assay
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Immobilized HER2/CD340 Protein, Human (HEK293, His, HY-P70254) can bind Timigutuzumab. The EC50 for this effect is 5.834 ng/mL. -
Flow cytometric analysis of 1×106 MCF-7 cells with Timigutuzumab (HY-P99558, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
化学情報
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CAS 番号 1665274-14-5
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性状 Liquid
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分子量 145.32 kDa
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Color Colorless to light yellow
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SMILES
[Timigutuzumab]
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別名
GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (256 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)