Tipifarnib (Standard)
Tipifarnib (Standard) is the analytical standard of Tipifarnib (HY-10502). This product is intended for research and analytical applications. Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 95%
- CAS 番号: 192185-72-1
- 分子式: C27H22Cl2N4O
- 分子量:489.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-10502
TipifarnibFTase Inhibitor -
HY-15136
LonafarnibFarnesyltransferase Inhibitor -
HY-15872A
FTI-277 hydrochlorideFTase Inhibitor -
HY-50876
DaporinadNMPRT Inhibitor -
HY-10038
A 922500DGAT-1 Inhibitor -
HY-16273A
L-778123 hydrochlorideFarnesyl Transferase Inhibitor -
HY-17406
TolcaponeCOMT Inhibitor -
HY-N6796
Manumycin AAntibiotic, TrxR-1 Inhibitor -
HY-15879
LB42708Farnesyltransferase Inhibitor -
HY-108467
GGsTopγ GGT Inhibitor -
HY-16373
CP-609754Farnesyltransferase Inhibitor -
HY-16273
L-778123FPTase/GGPTase-I Iinhibitor
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 192185-72-1
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分子量 489.40
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分子式 C27H22Cl2N4O
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SMILES
O=C1N(C2=C(C(C3=CC=CC(Cl)=C3)=C1)C=C(C=C2)[C@@](N)(C4=CN=CN4C)C5=CC=C(C=C5)Cl)C
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別名
IND 58359 (Standard); R115777 (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Devendra S Puntambekar, et al. Inhibition of farnesyltransferase: a rational approach to treat cancer? J Enzyme Inhib Med Chem. 2007 Apr;22(2):127-40. [Content Brief]
[2]. End DW, et al. Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro. Cancer Res. 2001 Jan 1;61(1):131-7 [Content Brief]
[3]. Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Tipifarnib (Standard) 関連分類
HY-10502R 関連分類
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