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製品番号: HY-D3415

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TOR-G4

TOR-G4 is a Fluorescent probe that binds to G-quadruplex (G4) nucleic acid structures. TOR-G4 exhibits a unique fluorescence lifetime when bound to G4 compared to other structures, enabling sensitive discrimination between G4-bound and non-G4-bound states. TOR-G4 mainly colocalizes with RNA in the cytoplasm and nucleolus. TOR-G4 can be used to investigate the roles of RNA G4 in cells. TOR-G4 shows cytotoxicity against osteosarcoma cells.

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CAS 番号: 3030070-69-7
分子式: C₃₀H₃₀IN₃OS
分子量:607.55

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

TOR-G4 構造式

CAS 番号: 3030070-69-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

TOR-G4 (6 h) exhibits cytotoxicity toward U2OS cells with a GI₅₀ of 143 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 3030070-69-7
分子量 607.55
分子式 C₃₀H₃₀IN₃OS
SMILES

CN(C)C(C=C1)=CC=C1/C=C/C2=C/C(C3=CC=CC=C3N2C)=C\C4=[N+](C)C5=C(C=CC(OC)=C5)S4.[I-]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Robinson J, et al. Cellular Visualization of G-Quadruplex RNA via Fluorescence- Lifetime Imaging Microscopy. J Am Chem Soc. 2024;146(1):1009-1018. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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