trans-ccc_R08
Based on 1 Customer Validation
trans-ccc_R08 (Compound 1-B) is a cccDNA inhibitor with anti-HBV activity, with an IC50 of 0.14 μM for HBeAg and an IC50 of 0.08 μM for HBsAg in in vitro assays. trans-ccc_R08 inhibits covalently closed circular DNA (cccDNA). trans-ccc_R08 is applicable to research related to hepatitis B virus infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.71%
- CAS 番号: 2413192-49-9
- 分子式: C22H19ClO6
- 分子量:414.84
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
trans-ccc_R08 inhibits HBeAg production in HepDES19 cells with an IC50 of 0.14 μM[1].
trans-ccc_R08 inhibits HBsAg production in cryopreserved primary hepatocytes, with an IC50 of 0.08 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2413192-49-9
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性状 Solid
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分子量 414.84
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分子式 C22H19ClO6
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Color Off-white to light yellow
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SMILES
O=C1C=C(C2=CC=C(C=C2)OCCO[C@@H]3C[C@H](C3)C(O)=O)OC4=C(Cl)C=CC=C41
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : 100 mg/mL (241.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4106 mL | 12.0528 mL | 24.1057 mL | 60.2642 mL |
| 5 mM | 0.4821 mL | 2.4106 mL | 4.8211 mL | 12.0528 mL | |
| 10 mM | 0.2411 mL | 1.2053 mL | 2.4106 mL | 6.0264 mL | |
| 15 mM | 0.1607 mL | 0.8035 mL | 1.6070 mL | 4.0176 mL | |
| 20 mM | 0.1205 mL | 0.6026 mL | 1.2053 mL | 3.0132 mL | |
| 25 mM | 0.0964 mL | 0.4821 mL | 0.9642 mL | 2.4106 mL | |
| 30 mM | 0.0804 mL | 0.4018 mL | 0.8035 mL | 2.0088 mL | |
| 40 mM | 0.0603 mL | 0.3013 mL | 0.6026 mL | 1.5066 mL | |
| 50 mM | 0.0482 mL | 0.2411 mL | 0.4821 mL | 1.2053 mL | |
| 60 mM | 0.0402 mL | 0.2009 mL | 0.4018 mL | 1.0044 mL | |
| 80 mM | 0.0301 mL | 0.1507 mL | 0.3013 mL | 0.7533 mL | |
| 100 mM | 0.0241 mL | 0.1205 mL | 0.2411 mL | 0.6026 mL |
trans-ccc_R08 関連分類
HY-148560A 関連分類
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