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製品番号: HY-103341

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UCM707

Name: UCM707
Brand: MedChemExpress
SKU: HY-103341
Price: 71.00 USD
Availability: InStock
Rating: 5 (1 reviews)

UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of Anandamide.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 390824-20-1
分子式: C₂₅H₃₇NO₂
分子量:383.57

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (259 KB)

UCM707 構造式

CAS 番号: 390824-20-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of Anandamide^[1].

Cannabinoid Receptor アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
U-937	IC₅₀	0.8 μM Compound: 42	Concentration required to inhibit anandamide uptake in U937 cell line Concentration required to inhibit anandamide uptake in U937 cell line	[PMID: 16078824]
U-937	IC₅₀	0.8 μM Compound: 5	Inhibition of [3H]anandamide transport(ANT) in human lymphoma U937 cell Inhibition of [3H]anandamide transport(ANT) in human lymphoma U937 cell	[PMID: 12672252]
U-937	IC₅₀	0.8 μM Compound: 9	Ability to inhibit [3H]anandamide uptake in human lymphoma U937 cells Ability to inhibit [3H]anandamide uptake in human lymphoma U937 cells	[PMID: 11741470]
U-937	IC₅₀	1.46 μM Compound: UCM707	Inhibition of [ethanol-amine-1-3H]AEA uptake in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting Inhibition of [ethanol-amine-1-3H]AEA uptake in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting	[PMID: 24972328]
U-937	IC₅₀	7.24 μM Compound: UCM707	Inhibition of FAAH-mediated [ethanol-amine-1-3H]AEA hydrolysis in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting Inhibition of FAAH-mediated [ethanol-amine-1-3H]AEA hydrolysis in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting	[PMID: 24972328]

化学情報

CAS 番号 390824-20-1
分子量 383.57
分子式 C₂₅H₃₇NO₂
SMILES

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NCC1=COC=C1)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (259 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Eva de Lago, et al. UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide. Eur J Pharmacol. 2002 Aug 2;449(1-2):99-103. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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