YM-254891
YM-254891 is a YM-254890 (HY-111557) analogue and Gαq/11 inhibitor. YM-254891 can be isolated from the fermentation broth of Chromobacterium sp. QS3666. YM-254891 inhibits ADP-induced platelet aggregation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 726188-99-4
- 分子式: C47H71N7O15
- 分子量:974.10
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Microbial Metabolite |
YM-254891 inhibits 2MeSADP-induced Ca2+ influx in P2Y1-C6-15 cells with an IC50 of 0.23 μM[1].
YM-254891 inhibits ADP-induced platelet aggregation in platelet-rich plasma with an IC50 of 0.27 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 726188-99-4
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分子量 974.10
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分子式 C47H71N7O15
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SMILES
CCC(N[C@@H]([C@H](O)C(C)C)C(O[C@@H]([C@@]1([H])C(N([C@@](C(O[C@@H]([C@@H](C(O[C@@H](C(N(C(C(N[C@H](C(N([C@H](C(N1)=O)C)C)=O)C)=O)=C)C)=O)CC2=CC=CC=C2)=O)NC(C)=O)C)=O)([H])[C@@H](C)OC)C)=O)C(C)C)=O)=O
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Structure Classification
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Initial Source
Chromobacterium sp
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)