JPM-OEt (Standard)
JPM-OEt (Standard) is the analytical standard of JPM-OEt (HY-102087). This product is intended for research and analytical applications. JPM-OEt is a broad spectrum cysteine cathepsin inhibitor. JPM-OEt binds covalently in the active site, and irreversibly inhibits the cysteine cathepsin family. Antitumor activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 262381-84-0
- 分子式: C20H28N2O6
- 分子量:392.45
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
化学情報
- 純度とドキュメンテーション
-
Help & FAQs
-
HY-D0843
N-EthylmaleimideCysteine Residues Modifier -
HY-148905
p-Aminophenylmercuric acetateMatrix Metalloproteinases Activator -
HY-100350
CA-074 methyl esterCathepsin B Inhibitor -
HY-15533
LY 3000328Cathepsin S Inhibitor -
HY-10042
OdanacatibCathepsin K Inhibitor -
HY-15100
BalicatibCathepsin K Inhibitor -
HY-103352
L-006235Cathepsin K Inhibitor -
HY-N2905
Aurantiamide acetateCathepsin Inhibitor -
HY-100231
Cathepsin inhibitor 1Cathepsin Inhibitor -
HY-109069
PetesicatibCathepsin S Inhibitor -
HY-118762
KGP94Cathepsin L Inhibitor -
HY-102087
JPM-OEtCysteine Cathepsin Inhibitor
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
-
CAS 番号 262381-84-0
-
分子量 392.45
-
分子式 C20H28N2O6
-
SMILES
O=C([C@H]1O[C@@H]1C(N[C@H](C(NCCC2=CC=C(O)C=C2)=O)CC(C)C)=O)OCC
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Withana NP, et al. Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Res. 2012 Mar 1;72(5):1199-209. [Content Brief]
[2]. Bell-McGuinn KM, et al. Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer. Cancer Res. 2007 Aug 1;67(15):7378-85. [Content Brief]
[3]. Schurigt U, et al. Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model. Biol Chem. 2008 Aug;389(8):1067-74. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
JPM-OEt (Standard) 関連分類
HY-102087R 関連分類
Powered by Bioz