1. Stem Cell/Wnt
  2. Smo
  3. KAAD-Cyclopamine

KAAD-Cyclopamine (Synonyms: Cyclopamine-KAAD)

Cat. No.: HY-100535
Handling Instructions

KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist.

For research use only. We do not sell to patients.

KAAD-Cyclopamine Chemical Structure

KAAD-Cyclopamine Chemical Structure

CAS No. : 306387-90-6

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KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist[1].

In Vitro

KAAD-Cyclopamine inhibits pathway activation induced by 1 μM purmorphamine with an IC50 of 3 nM, wheras this cyclopamine derivative has an IC50 of 100 nM in Shh-LIGHT2 cells stimulated with 10 μM purmorphamine[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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