2. KAAD-Cyclopamine

KAAD-Cyclopamine  (Synonyms: Cyclopamine-KAAD)

Cat. No.: HY-100535 Purity: ≥96.0%
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KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist.

For research use only. We do not sell to patients.

KAAD-Cyclopamine Chemical Structure

KAAD-Cyclopamine Chemical Structure

CAS No. : 306387-90-6

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25 μg USD 170 In-stock
50 μg USD 270 In-stock

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KAAD-Cyclopamine Related Antibodies

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Description

KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist[1].

In Vitro

KAAD-Cyclopamine inhibits pathway activation induced by 1 μM purmorphamine with an IC50 of 3 nM, wheras this cyclopamine derivative has an IC50 of 100 nM in Shh-LIGHT2 cells stimulated with 10 μM purmorphamine[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

KAAD-Cyclopamine Related Antibodies
Molecular Weight

697.99

Formula

C44H63N3O4
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

C[C@H]([C@@](N1CCNC(CCCCCNC(CCC2=CC=CC=C2)=O)=O)([H])[C@](C[C@H](C)C1)([H])O3)[C@@]43C(C)=C(C[C@@]5([H])[C@@]6([H])CC=C(C7)[C@@]5(CCC7=O)C)[C@@]6([H])CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥96.0%

COA (246 KB) Elemental Analysis Report (103 KB)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KAAD-Cyclopamine306387-90-6Cyclopamine-KAADInhibitorinhibitorinhibit

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