Kadsuphilin A
Kadsuphilin A can be extracted from Kadsura coccinea (Lem.) and has weak antiproliferative activity.
For research use only. We do not sell to patients.
- CAS No.: 887770-02-7
- Formula: C32H34O8
- Molecular Weight:546.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | ED50 |
≥5 μg/mL
Compound: 1
|
Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
|
[PMID: 16792420] |
| KB | ED50 |
≥5 μg/mL
Compound: 1
|
Cytotoxicity against human KB cells by MTT assay
Cytotoxicity against human KB cells by MTT assay
|
[PMID: 16792420] |
Chemical Information
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CAS No. 887770-02-7
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Molecular Weight 546.61
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Formula C32H34O8
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SMILES
O=C(/C=C/C1=CC=CC=C1)O[C@H]2C3=C(C4=C(C(OC)=C(C=C4C[C@H]([C@H]2C)C)OC)OC)C(OC)=C5OCOC5=C3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)