KB 5666
KB 5666 is a benzoxazine derivative with lipid peroxidation inhibitory activity. KB 5666 showed protective effects against post-ischemic neuronal death. KB 5666 effectively protected CA1 neurons when injected 5 minutes before or immediately after ischemia. KB 5666 also showed a dose-dependent protective effect when injected within 1 hour after ischemia. KB 5666 effectively prevented the significant decrease in microtubule-associated protein 2 immunoreactivity within the dendritic field of CA1 pyramidal cells. KB 5666 prevented the decrease in [3H]PDBu binding activity in different layers of the CA1 region after ischemia. The application of KB 5666 showed the ability to improve the cellular and functional consequences of ischemia.
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- CAS No.: 131916-69-3
- Formule: C24H32N4O5
- Masse moléculaire:456.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 131916-69-3
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Masse moléculaire 456.53
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Formule C24H32N4O5
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SMILES
C=CCN1CCN(CC1)C2=NC(OCCCCC)=C3C=CC=CC3=N2.O=C(/C=C/C(O)=O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KB 5666 Related Classifications
HY-117578 Related Classifications
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