Kidney-targeting peptide
Based on 1 Customer Validation
Kidney-targeting peptide is a kidney-targeting peptide (KTP). Kidney-targeting peptide significantly enhances the renal targeting ability of Isoquercitrin (HY-N1445). Kidney-targeting peptide can be used in diabetic nephropathy research.
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 3106628-25-2
- Formula: C90H154N24O36S
- Molecular Weight:2180.39
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Unstated strain (male, used for in vivo biodistribution studies)[1]
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Dosage:300 μg/mL isoquercitrin equivalent dose
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Administration:i.v.; single injection
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Result:Achieved significantly higher renal fluorescence signal (drug accumulation) compared to non-KTP-containing control nanocarriers at 6, 12, and 18 hours post-administration.
Exhibited significantly lower fluorescence signal in heart, liver, spleen, and lungs compared to non-KTP-containing control nanocarriers at 6, 12, and 18 hours post-administration.
Achieved a renal targeting efficiency of 20% ID/g.
Chemical Information
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CAS No. 3106628-25-2
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Appearance Solid
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Molecular Weight 2180.39
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Formula C90H154N24O36S
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Color White to off-white
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Sequence
Cys-Lys-Lys-Glu-Glu-Glu-Lys-Lys-Glu-Glu-Glu-Lys-Lys-Glu-Glu-Glu-Lys
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Sequence Shortening
CKKEEEKKEEEKKEEEK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 25 mg/mL (11.47 mM; Need ultrasonic)
DMSO : 25 mg/mL (11.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 0.4586 mL | 2.2932 mL | 4.5863 mL | 11.4658 mL |
| 5 mM | 0.0917 mL | 0.4586 mL | 0.9173 mL | 2.2932 mL | |
| 10 mM | 0.0459 mL | 0.2293 mL | 0.4586 mL | 1.1466 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Kidney-targeting peptide Related Classifications
HY-P11069 Related Classifications
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