CHBO4
CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research.
For research use only. We do not sell to patients.
- CAS No.: 98991-32-3
- Formula: C15H10BrFO
- Molecular Weight:305.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hMAO-B 0.031 μM (IC50) |
hMAO-B 0.010 μM (Ki) |
CHBO4 (10-500 µg/mL, 48 h) is biologically safe in Vero cells[1].
CHBO4 (128.8 µg/mL, 10 min) can reduce ROS generation in Vero cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Vero cells
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Concentration:10-500 µg/mL
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Incubation Time:48 h
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Result:Reduced cell viability percentage with the IC50 value of 128.8 µg/mL
Decreased cellular density, cellular shrinkage, and blebbing exposed to concentrations (100-300 µg/mL) in Vero cells
Chemical Information
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CAS No. 98991-32-3
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Molecular Weight 305.14
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Formula C15H10BrFO
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SMILES
BrC1=CC=C(C(/C=C/C2=CC=C(F)C=C2)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CHBO4 Related Classifications
HY-155137 Related Classifications
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