Map1a - microtubule-associated protein 1A Gene

Also Known as Mtap1a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25152

Summary

Enables actin binding activity; Collagen binding activity; and microtubule binding activity. Involved in negative regulation of microtubule depolymerization. Located in several cellular components, including axon; dendrite; and neuronal cell body. Part of microtubule associated complex. Biomarker of hypothyroidism. Orthologous to human MAP1A (microtubule associated protein 1A). [provided by Alliance of Genome Resources, Apr 2022]

Map1a Products (1)

mRNA Protein Name
NM_030995.2 NP_112257.2 microtubule-associated protein 1A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
11896150 RGD
enables collagen binding IPI
IPI: Inferred from physical interaction
11418592 RGD
enables microtubule binding IDA
IDA: Inferred from direct assay
9627185 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
7908909 RGD
enables structural constituent of presynapse IDA
IDA: Inferred from direct assay
18971475 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of microtubule depolymerization IDA
IDA: Inferred from direct assay
11896150 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
9627185 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
2509111 RGD
located in dendrite IDA
IDA: Inferred from direct assay
9627185 RGD
located in dendritic branch IDA
IDA: Inferred from direct assay
2509111 RGD
located in dendritic shaft IDA
IDA: Inferred from direct assay
2509111 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
18971475 RGD
part of microtubule associated complex IDA
IDA: Inferred from direct assay
7908909 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
9627185 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
9627185 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
18971475 RGD
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
18971475 RGD
located in primary dendrite IDA
IDA: Inferred from direct assay
2509111 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated protein 1A

  • MAP-1A

Map1a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Map1a P34926 Dlg4 Rattus norvegicus P31016
Filter Binding
9786987
Intra
Map1a P34926 Dlg4 Rattus norvegicus P31016
Fluorescence Spectr
17220895
Intra
Map1a P34926 Dlg4 Rattus norvegicus P31016
Pull Down
9786987
Intra
Map1a P34926 Dlg4 Rattus norvegicus P31016
Far-WB
9786987
Intra
Map1a P34926 Dlg4 Rattus norvegicus P31016
Y2H
9786987
Intra
Map1a P34926 Dlg1 Rattus norvegicus Q62696
Pull Down
9786987
Intra
Map1a P34926 Dlg2 Rattus norvegicus Q63622
Anti Bait CoIP
9786987
Intra
Map1a P34926 Dlg2 Rattus norvegicus Q63622
IF
9786987
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08026 MAP1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08348 METAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18394 Map1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24875 Map1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map1a NCBI NCBI:4130