Ipsoprubart
Based on 1 Customer Validation
Ipsoprubart is a humanized IgG1κ antibody targeting SIRPa/CD172a. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001).
For research use only. We do not sell to patients.
- Purity : 97%
- CAS No.: 3035552-25-8
- Molecular Weight:145.268 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
SIRPa/CD172a
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Loaded Ipsoprubart on ProA biosensor, can bind HY-P76068 SIRPalpha V8/CD172a Protein, Human (AAH38510, HEK293, His) with an affinity constant of 3.197E-09 M as determined in BLI assay.
Chemical Information
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CAS No. 3035552-25-8
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Appearance Liquid
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Molecular Weight 145.268 kDa
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Color Colorless to light yellow
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SMILES
N/A
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Synonyms
ELA-026
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (254 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)