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Cat. No.: HY-155284

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K1833

K1833 is a hrAChE inhibitor/reactivator, with an IC₅₀ of 58 μM. K1833 also shows high inhibition (IC₅₀=0.57μM) and low reactivation for hrBChE.

For research use only. We do not sell to patients.

Formula: C₂₆H₂₈BBr₂F₂N₇O₂
Molecular Weight:679.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

K1833 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

K1833 is a hrAChE inhibitor/reactivator, with an IC₅₀ of 58 μM. K1833 also shows high inhibition (IC₅₀=0.57μM) and low reactivation for hrBChE^[1].

IC₅₀ & Target^[1]

hAChE

58 μM (IC₅₀)

hBCHE

0.57 μM (IC₅₀)

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

Molecular Weight 679.16
Formula C₂₆H₂₈BBr₂F₂N₇O₂
SMILES

FB1(F)N2C=CC=C2C(NCCNC(C3=CC=[N+](CCC[N+]4=CC=C(/C=N/O)C=C4)C=C3)=O)=C5C=CC=[N]15.[Br-].[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Prchalova E, et, al. BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS. Biomed Pharmacother. 2023 Nov:167:115490. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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K1833

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

K1833 Related Classifications

HY-155284 Related Classifications