IL-9
Interleukin-9 (IL-9) is a 14 kDa glycoprotein classified within the hematopoietin family, historically termed T-cell growth factor III and mast cell growth-enhancing factor. IL-9 is secreted predominantly by Th9 cells, a distinct T-helper lineage induced from Th2 precursors by IL-4 plus TGF-β, and also by group 2 innate lymphoid cells and mast cells. It signals via IL-9Rα coupled to the common gamma chain, engaging JAK1/JAK3-STAT5, STAT6 and STAT3. IL-9 promotes mast cell proliferation and IgE responses, enhances mucus secretion and goblet cell hyperplasia, and supports eosinophil survival, linking it to allergic airway inflammation, asthma and parasitic immunity. Emerging evidence also implicates IL-9 in antitumor immunity through its effects on mast cells and CD8+ T cells.
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IL-9 Recombinant Proteins (11)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
