18:0 mPEG2000 PE
Based on 1 publication(s) in Google Scholar
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG2000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (2 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG2000 PE ammonium can be used for the research of nanoprobes and drug delivery.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.43%
- CAS No.: 156543-00-9
- 화학식: (C2H4O)nC43H84NO10P
- 분자량:2000(Average)
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 18:0 mPEG2000 PE
More
Biological Activity
18:0 mPEG2000 PE ammonium is used to synthesize a highly sensitive and selective fluorescent probe (BANP) for detecting dibutyl phthalate (DBP)[1].
18:0 mPEG2000 PE ammonium is used to prepare near-infrared II (NIR-II) scaffold molecular dye (SYL) and to prepare it into a nanoprobe for tumor imaging and photothermal therapy[2].
18:0 mPEG2000 PE ammonium is used to synthesize organic nanoparticles targeting lysosomes for photoacoustic imaging and photodynamic anticancer research under near-infrared light[3].
18:0 mPEG2000 PE ammonium is used to develop a nanoprobe based on a platinum (II) metal ring in the second near-infrared region (NIR-II), integrating fluorescence imaging and chemotherapy[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 156543-00-9
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Appearance Solid
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분자량 2000(Average)
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화학식 (C2H4O)nC43H84NO10P
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Color White to off-white
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SMILES
O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O)OCCOC.[n]
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Synonyms
DSPE-mPEG2000
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Int J Nanomedicine
IR-820@NBs Combined with MG-132 Enhances the Anti-Hepatocellular Carcinoma Effect of Sonodynamic Therapy. [Abstract]2023 Nov 1:18:6199-6212. PMID: 37933299
용액&용해도
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
순도&문서
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Lu JY, et al. A dye-andrographolide assembly as a turn-on sensor for detection of phthalate in both cells and fish. Anal Chim Acta. 2022 Feb 22;1195:339460. [Content Brief]
[2]. Zhang R, et al. Rational design of a multifunctional molecular dye for dual-modal NIR-II/photoacoustic imaging and photothermal therapy. Chem Sci. 2019 Jul 30;10(36):8348-8353. [Content Brief]
[3]. Hu W, et al. Engineering Lysosome-Targeting BODIPY Nanoparticles for Photoacoustic Imaging and Photodynamic Therapy under Near-Infrared Light. ACS Appl Mater Interfaces. 2016 May 18;8(19):12039-47. [Content Brief]
[4]. Sun Y, et al. Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1968-1973. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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